Developing better tests for earlier diagnosis of secondary breast cancer to increase survival rates.
Research projects that are associated with our research theme of Detection are shown below:
ABC Discover 2
Prof Paul Skipp, University of Southampton
ABC Discover 2, led by Professor Paul Skipp at the University of Southampton, aims to transform secondary breast cancer research across the three ABC research themes of detection, therapy, and prevention, utilising the DietCompLyf Biobank.
ABC Discover
Prof Paul Skipp, University of Southampton
ABC Discover completed a highly successful 5-year period in 2025 with multiple breakthroughs achieved across the three pillars of ABC research: prevention, earlier detection, and better treatments of secondary breast cancer.
Characterising the Glycan Shield
Dr Oliver Pearce, Barts Cancer Institute, London
Dr. Oliver Pearce aims to identify how breast cancer tumours remodel their surroundings to protect them from attack by the bodies’ own immune system. He hopes to understand how immune cells are deactivated in order to improve the response to immunotherapy in triple negative breast cancer patients.
Exploring Versican as an Immune Barrier in Cancer
Dr Oliver Pearce and Priyanka Hirani, Barts Cancer Institute, London
Following on from the Glycan Shield project, Dr. Oliver Pearce and Priyanka Hirani are investigating how the protein Versican might be involved in deactivating immune cells in the tumour microenvironment.
Dr Miriam Dwek, University of Westminster
As part of our DietCompLyf study biological samples of blood and urine were collected to form a biobank that will be used in ABC Discover 2.