How the body’s natural defences could be harnessed to design more effective treatments and ultimately a vaccine against breast cancer.
Research projects that are associated with our research theme of Therapies are shown below:
ABC Discover 2
Prof Paul Skipp, University of Southampton
ABC Discover 2, led by Professor Paul Skipp at the University of Southampton, aims to transform secondary breast cancer research across the three ABC research themes of detection, therapy, and prevention, utilising the DietCompLyf Biobank.
The Impact of Obesity on Immune Modulation in Breast Cancer Metastasis and Immunotherapy Outcomes
Dr Charles Birts, University of Southampton
The Fellowship project is investigating how obesity influences breast cancer progression, particularly cancer spread and treatment response.
Therapeutic Antibody Programme
Prof Max Crispin, University of Southampton
Against Breast Cancer’s first long-term programme grant will support innovative research in the development of antibody therapies for secondary breast cancer.
Investigating whether tertiary lymphoid structures in breast cancer are engines of anti-tumour immunity
Dr Isabela Pedroza-Pacheco, University of Oxford
Dr Isabela Pedroza-Pacheco will investigate anti-tumour immunity by applying advanced proteomic and gene expression technologies to analyse tissues and cells obtained from breast cancer patients.
Investigating how the tumour extracellular matrix drives immune suppression in triple-negative breast cancer
Dr Ludovica Tarantola, Barts Cancer Institute
Ludovica’s PhD research has focused on understanding how the tumour environment affects immune cells and prevents them from effectively fighting breast cancer.